Just about everything outside the female reproductive tract kills sperm, including lubricants. But sometimes lubricant is desirable during sex. In 2008, an independent lab at the Cleveland Clinic headed by Ashok Agarwal published in the journal of Fertility and Sterility a comparison of different lubricants and how they degrade sperm movement and the DNA that the sperm contains. Of Pre-Seed, FemGlide, Astroglide, and Replens, Pre-Seed was the one that didn’t seem to have much negative effect on sperm motion and DNA. So, if you’re going to use lubricant during sex and you want to conceive, Pre-Seed seems to be a good choice. (I have absolutely no relationship, financial or otherwise, to the company that makes it.)
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